Future University In Egypt (FUE)
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Altagamoa Al Khames, Main centre of town, end of 90th Street
New Cairo
Egypt

Raghda Talal

Basic information

Name : Raghda Talal
Title: Teaching Assistant
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Personal Info: Teaching Assistant: Raghda Talal, Teaching Assistant in Pharmacology and Toxicology and Biochemistry department.

Education

Certificate Major University Year
Masters Pharmaclogy & Toxicology suez canal university - Faculty of pharmacy 2017
Bachelor . Cairo University - Faculty of Pharmacy 2005

Teaching Experience

Name of Organization Position From Date To Date
AlKan Pharma Regulatory Affairs Coordinator 01/02/2007 10/10/2009
International Garden Pharmacy Pharmacist 01/12/2005 01/05/2006
Hala Pharmacy Pharmacist 01/07/2005 01/11/2006

Researches /Publications

The anorectic agent, lorcaserin, disturbs estrous cyclicity and produces endometrial hyperplasia without affecting ovarian population in female rats. - 01/0

Raghda Talal Abdellatif Taha Hassanin

Sawsan A.Zaitone

01/08/2017

Aims The present study aims to investigate the effect of the new anorectic agent, lorcaserin, on estrous cyclicity, reproductive hormones and folliculogenesis in female mature rats. Materials and methods Rats were divided into four groups; Group i: control group. Group ii-iv: rats treated with lorcaserin (5, 10 or 30 mg/kg/day, p.o.), respectively. The treatment continued for 28 days. Key findings Lorcaserin (5 or 10 mg/kg) caused estrous cycle disturbance in 40% of treated rats while the high dose (30 mg/kg) produced disturbances in 100% of the treated rats. Lorcaserin (5–30 mg/kg) altered some of female hormones where it enhanced estradiol but reduced luteinizing hormone. Minimal edema with congested vessels was observed in the medulla of ovarian sections. Further, epithelial and uterine sections showed hyperplasia. Significance Taken together, the present results demonstrated that lorcaserin affected some reproductive hormones, disturbed estrous cyclicity and induced histopathological changes in the ovaries and uteri without affecting the ovarian populations. Therefore, lorcaserin should be used with caution in women of child bearing potential until adequate clinical safety data are available.

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